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Boster Bio
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InterPro Inc
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Ferdinand Kreutzer Sabamuhle
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Image Search Results
Journal: International Journal of Dermatology and Venereology
Article Title: Oxyresveratrol-induced Activation of Nrf2/HO-1 Signaling Pathway Enhances Ability of Resveratrol to Inhibit UVB-induced Melanin
doi: 10.1097/jd9.0000000000000135
Figure Lengend Snippet: Figure 2. Effects of UVB irradiation on antioxidant genes and melanogenic genes in PIG1 cells. (A) Irradiation with 300 mJ/cm2 of UVB increased the mRNA expression levels of Nrf2 and HO-1 compared with the control group. (B) Western blot analysis demonstrated that after UVB irradiation, the protein expression of Nrf2 and HO-1 was higher than that in the control group. (C) The mRNA levels of MITF, TYR, TRP1, and TRP2 were higher than those in the control group. (D) The protein expression levels of MITF, TYR, TRP1, and TRP2 were determined through western blot analysis. ∗∗P < 0.01, ∗P < 0.05 vs. control group; n = 3. UVB: ultraviolet B; TYR: tyrosinase; TRP: TYR-related protein; MITF: melanocyte-inducing transcription factor.
Article Snippet: The following antibodies were applied: b-actin (K101527P; Solarbio, Beijing, China); Nrf2 (#12721), TYR (#11873), and HO-1 (#5853) (Cell Signaling Technology, Danvers, MA, USA); melanocyte-inducing transcription factor (MITF) (ab20663),
Techniques: Irradiation, Expressing, Control, Western Blot